SLC35B2 solute carrier family 35 member B2 [ Homo sapiens (human) ] - Gene - Data resources

347734

SLC35B2 solute carrier family 35 member B2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 347734)

Symbol: SLC35B2

Full name: solute carrier family 35 member B2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: PAPST1; SLL; UGTrel4

Summary: Sulfotransferases (e.g., SULT4A1; MIM 608359) use an activated form of sulfate, 3-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS), as a common sulfate donor for sulfation of glycoproteins, proteoglycans, and glycolipids in the endoplasmic reticulum and Golgi apparatus. SLC35B2 is located in the microsomal membrane and transports PAPS from the cytosol, where it is synthesized, into the Golgi lumen (Kamiyama et al., 2003 [PubMed 12716889]).[supplied by OMIM, Mar 2008]

Expression: Ubiquitous expression in gall bladder (RPKM 17.2), thyroid (RPKM 15.1) and 25 other tissues

Orthologs: mouse

Gene size: 3790bp

Exon count: 6