Full name: homeobox B7

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: HHO.C1; HOX2; HOX2C; Hox-2.3

Summary: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]

Expression: Broad expression in kidney (RPKM 10.0), colon (RPKM 8.7) and 15 other tissues

Gene size: 3786bp

Exon count: 2