Full name: homeobox A9

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ABD-B; HOX1; HOX1.7; HOX1G

Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.[provided by RefSeq, Mar 2011]

Expression: Biased expression in kidney (RPKM 13.0), endometrium (RPKM 8.0) and 11 other tissues

Gene size: 3100bp

Exon count: 2