Full name: homeobox A1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BSAS; HOX1; HOX1F

Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008]

Expression: Biased expression in urinary bladder (RPKM 4.0), skin (RPKM 1.0) and 13 other tissues

Gene size: 3008bp

Exon count: 3