Full name: acyloxyacyl hydrolase

Gene type: protein coding

RefSeq status: REVIEWED

Summary: This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]

Expression: Biased expression in spleen (RPKM 9.9), appendix (RPKM 5.8) and 13 other tissues

Gene size: 211554bp

Exon count: 29