Full name: annexin A4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ANX4; HEL-S-274; P32.5; PAP-II; PIG28; PP4-X; ZAP36

Summary: Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]

Expression: Broad expression in gall bladder (RPKM 187.6), duodenum (RPKM 64.1) and 17 other tissues

Gene size: 183305bp

Exon count: 22