BRF1 BRF1 RNA polymerase III transcription initiation factor subunit [ Homo sapiens (human) ]
Source: NCBI Gene (ID 2972)
Source: NCBI Gene (ID 2972)
Symbol: BRF1
Full name: BRF1 RNA polymerase III transcription initiation factor subunit
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: BRF; BRF-1; CFDS; GTF3B; HEL-S-76p; TAF3B2; TAF3C; TAFIII90; TF3B90; TFIIIB90; hBRF
Summary: This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]
Expression: Ubiquitous expression in fat (RPKM 3.5), brain (RPKM 3.4) and 25 other tissues
Orthologs: mouse
Gene size: 106304bp
Exon count: 25