Full name: Rac GTPase activating protein 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CDAN3B; CYK4; HsCYK-4; ID-GAP; MgcRacGAP

Summary: This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]

Expression: Broad expression in testis (RPKM 17.3), bone marrow (RPKM 8.3) and 20 other tissues

Gene size: 44279bp

Exon count: 23