Full name: ABR activator of RhoGEF and GTPase

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MDB

Summary: This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Feb 2012]

Expression: Ubiquitous expression in brain (RPKM 31.0), heart (RPKM 11.9) and 23 other tissues

Gene size: 226204bp

Exon count: 37