Full name: growth factor receptor bound protein 14

Gene type: protein coding

RefSeq status: REVIEWED

Summary: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Expression: Biased expression in kidney (RPKM 7.9), liver (RPKM 7.8) and 12 other tissues

Gene size: 129066bp

Exon count: 16