GRB7 growth factor receptor bound protein 7 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 2886)
Symbol: GRB7
Full name: growth factor receptor bound protein 7
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Summary: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Expression: Broad expression in kidney (RPKM 6.4), esophagus (RPKM 5.5) and 16 other tissues
Orthologs: mouse
Gene size: 9348bp
Exon count: 18