FBXO43 F-box protein 43 [ Homo sapiens (human) ] - Gene - Data resources

286151

FBXO43 F-box protein 43 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 286151)

Symbol: FBXO43

Full name: F-box protein 43

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: EMI2; ERP1; FBX43; OOMD12; SPGF64

Summary: Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Expression: Biased expression in testis (RPKM 4.9), lymph node (RPKM 0.6) and 2 other tissues

Orthologs: mouse

Gene size: 17219bp

Exon count: 8