Tinf2 Terf1 (TRF1)-interacting nuclear factor 2 [ Mus musculus (house mouse) ] - Gene - Data resources

28113

Tinf2 Terf1 (TRF1)-interacting nuclear factor 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 28113)

Symbol: Tinf2

Full name: Terf1 (TRF1)-interacting nuclear factor 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: D14Wsu146e; Tin2

Summary: Enables telomeric DNA binding activity. Acts upstream of or within negative regulation of telomere maintenance. Located in chromosome, telomeric region. Is expressed in several structures, including brain ventricular layer; olfactory epithelium; submandibular gland primordium; thymus primordium; and vibrissa. Used to study dyskeratosis congenita. Human ortholog(s) of this gene implicated in Revesz syndrome and autosomal dominant dyskeratosis congenita 3. Orthologous to human TINF2 (TERF1 interacting nuclear factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 11.0), placenta adult (RPKM 8.2) and 28 other tissues

Orthologs: human

Gene size: 5638bp

Exon count: 10