Skp2 S-phase kinase-associated protein 2 [ Mus musculus (house mouse) ] - Gene - Data resources

27401

Skp2 S-phase kinase-associated protein 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 27401)

Symbol: Skp2

Full name: S-phase kinase-associated protein 2

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 4930500A04Rik; FBXL1; FWD1; p45

Summary: Predicted to enable identical protein binding activity. Acts upstream of or within several processes, including cellular protein metabolic process; mitotic cell cycle phase transition; and positive regulation of intracellular estrogen receptor signaling pathway. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including blastocyst; compacted morula; and retina nuclear layer. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human SKP2 (S-phase kinase associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in testis adult (RPKM 26.1), limb E14.5 (RPKM 12.8) and 9 other tissues

Orthologs: human

Gene size: 43443bp

Exon count: 12