TOX3 TOX high mobility group box family member 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 27324)
Symbol: TOX3
Full name: TOX high mobility group box family member 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: CAGF9; TNRC9
Summary: The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]
Expression: Biased expression in stomach (RPKM 5.0), colon (RPKM 3.6) and 13 other tissues
Orthologs: mouse
Gene size: 111387bp
Exon count: 10