Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 27279)
Source: NCBI Gene (ID 27279)
Symbol: Tnfrsf12a
Full name: tumor necrosis factor receptor superfamily, member 12a
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Fn14; HPIP; TWEAK-R; TweakR
Summary: Involved in regulation of angiogenesis. Acts upstream of or within extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Located in cell surface; plasma membrane; and ruffle. Is expressed in several structures, including adrenal medulla; genitourinary system; heart; limb long bone; and molar. Orthologous to human TNFRSF12A (TNF receptor superfamily member 12A). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in adrenal adult (RPKM 44.7), ovary adult (RPKM 38.8) and 18 other tissues
Orthologs: human
Gene size: 2005bp
Exon count: 4