MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 266727)
Source: NCBI Gene (ID 266727)
Symbol: MDGA1
Full name: MAM domain containing glycosylphosphatidylinositol anchor 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: GPIM; MAMDC3
Summary: This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest this protein plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2016]
Expression: Broad expression in brain (RPKM 2.6), ovary (RPKM 2.3) and 21 other tissues
Orthologs: mouse
Gene size: 67205bp
Exon count: 19