Full name: homer scaffolding protein 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: PSD-Zip45; SYN47; Ves-1; homer-1; vesl-1

Summary: Predicted to enable several functions, including scaffold protein binding activity; transmembrane transporter binding activity; and type 5 metabotropic glutamate receptor binding activity. Predicted to be a structural constituent of postsynapse. Involved in regulation of ion transport and regulation of postsynaptic neurotransmitter receptor activity. Acts upstream of or within several processes, including behavioral response to cocaine; chemical homeostasis within a tissue; and skeletal muscle fiber development. Located in several cellular components, including apical part of cell; myofibril; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human HOMER1 (homer scaffold protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in cortex adult (RPKM 6.9), frontal lobe adult (RPKM 5.3) and 24 other tissues

Gene size: 109207bp

Exon count: 12