Full name: phospholipase A2 group IID

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: PLA2IID; SPLASH; sPLA2-IID; sPLA2S

Summary: This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

Expression: Biased expression in lymph node (RPKM 63.3), appendix (RPKM 10.7) and 2 other tissues

Gene size: 7598bp

Exon count: 4