GAS2 growth arrest specific 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 2620)
Source: NCBI Gene (ID 2620)
Symbol: GAS2
Full name: growth arrest specific 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: GAS-2
Summary: The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017]
Expression: Broad expression in liver (RPKM 2.8), kidney (RPKM 0.9) and 21 other tissues
Orthologs: mouse
Gene size: 259694bp
Exon count: 22