ACOT11 acyl-CoA thioesterase 11 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 26027)
Symbol: ACOT11
Full name: acyl-CoA thioesterase 11
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: BFIT; STARD14; THEA; THEM1
Summary: This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Expression: Biased expression in kidney (RPKM 35.3), small intestine (RPKM 20.0) and 9 other tissues
Orthologs: mouse
Gene size: 90965bp
Exon count: 18