GEMIN5 gem nuclear organelle associated protein 5 [ Homo sapiens (human) ] - Gene - Data resources

25929

GEMIN5 gem nuclear organelle associated protein 5 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 25929)

Symbol: GEMIN5

Full name: gem nuclear organelle associated protein 5

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: GEMIN-5; NEDCAM

Summary: This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Expression: Ubiquitous expression in testis (RPKM 4.9), ovary (RPKM 4.6) and 25 other tissues

Orthologs: mouse

Gene size: 50801bp

Exon count: 28