Full name: anaphase promoting complex subunit 13

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: APC13; SWM1

Summary: This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]

Expression: Ubiquitous expression in thyroid (RPKM 36.9), kidney (RPKM 32.9) and 25 other tissues

Gene size: 8320bp

Exon count: 3