Full name: BMP and activin membrane bound inhibitor

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: NMA

Summary: This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]

Expression: Broad expression in ovary (RPKM 40.8), adrenal (RPKM 26.5) and 15 other tissues

Gene size: 5412bp

Exon count: 3