Full name: RAB3 GTPase activating non-catalytic protein subunit 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MARTS1; RAB3-GAP150; RAB3GAP150; SPG69; WARBM2; p150

Summary: The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009]

Expression: Ubiquitous expression in thyroid (RPKM 9.2), brain (RPKM 7.7) and 25 other tissues

Gene size: 124161bp

Exon count: 35