Full name: gamma-aminobutyric acid type A receptor subunit alpha2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DEE78; EIEE78

Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Expression: Biased expression in brain (RPKM 13.5), kidney (RPKM 1.1) and 1 other tissue

Gene size: 146753bp

Exon count: 14