Oas3 2'-5' oligoadenylate synthetase 3 [ Mus musculus (house mouse) ] - Gene - Data resources

246727

Oas3 2'-5' oligoadenylate synthetase 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 246727)

Symbol: Oas3

Full name: 2'-5' oligoadenylate synthetase 3

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Oasl10

Summary: Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Predicted to be involved in several processes, including defense response to other organism; negative regulation of type I interferon-mediated signaling pathway; and regulation of cytokine production. Predicted to act upstream of or within innate immune response. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol; membrane; and nucleoplasm. Orthologous to human OAS3 (2'-5'-oligoadenylate synthetase 3). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in small intestine adult (RPKM 15.4), duodenum adult (RPKM 12.6) and 8 other tissues

Orthologs: human

Gene size: 24593bp

Exon count: 16