Full name: repulsive guidance molecule family member A

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: C230063O06

Summary: Enables coreceptor activity and signaling receptor binding activity. Acts upstream of or within several processes, including nervous system development; positive regulation of GTPase activity; and positive regulation of membrane protein ectodomain proteolysis. Located in cell surface. Is expressed in several structures, including future brain; gut; nervous system; sensory organ; and trunk somite. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human RGMA (repulsive guidance molecule BMP co-receptor a). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in whole brain E14.5 (RPKM 24.7), ovary adult (RPKM 23.2) and 23 other tissues

Gene size: 44380bp

Exon count: 5