Ldb3 LIM domain binding 3 [ Mus musculus (house mouse) ] - Gene - Data resources

24131

Ldb3 LIM domain binding 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 24131)

Symbol: Ldb3

Full name: LIM domain binding 3

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: PDLIM6; ZASP

Summary: Enables muscle alpha-actinin binding activity and protein kinase C binding activity. Acts upstream of or within sarcomere organization. Located in Z disc. Is expressed in several structures, including central nervous system; heart; lower urinary tract; musculature; and sensory organ. Used to study congenital myopathy; dilated cardiomyopathy 1C; and myofibrillar myopathy 1. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1C; distal myopathy; and myofibrillar myopathy 4. Orthologous to human LDB3 (LIM domain binding 3). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in heart adult (RPKM 122.1), mammary gland adult (RPKM 32.6) and 6 other tissues

Orthologs: human

Gene size: 63621bp

Exon count: 19