Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 238505)
Source: NCBI Gene (ID 238505)
Symbol: Mtr
Full name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: D830038K18Rik; MS
Summary: Enables methionine synthase activity. Acts upstream of or within methionine biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including eye; genitourinary system; integumental system; limb; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; hematologic cancer (multiple); hyperhomocysteinemia; and methylmalonic aciduria and homocystinuria type cblG. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in heart adult (RPKM 14.2), limb E14.5 (RPKM 5.2) and 22 other tissues
Orthologs: human
Gene size: 76874bp
Exon count: 33