Akt3 thymoma viral proto-oncogene 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 23797)
Source: NCBI Gene (ID 23797)
Symbol: Akt3
Full name: thymoma viral proto-oncogene 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: D930002M15Rik; Nmf350
Summary: Predicted to enable ATP binding activity; protein kinase C binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of angiogenesis and positive regulation of artery morphogenesis. Acts upstream of or within several processes, including brain morphogenesis; positive regulation of TOR signaling; and positive regulation of cell size. Predicted to be located in plasma membrane. Is expressed in several structures, including genitourinary system; musculature; nervous system; retina; and skin. Human ortholog(s) of this gene implicated in colon cancer; glioblastoma; prostate adenocarcinoma; prostate cancer; and renal cell carcinoma. Orthologous to human AKT3 (AKT serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E18 (RPKM 12.2), CNS E14 (RPKM 10.5) and 22 other tissues
Orthologs: human
Gene size: 244047bp
Exon count: 20