Slc9a6 solute carrier family 9 (sodium/hydrogen exchanger), member 6 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 236794)
Source: NCBI Gene (ID 236794)
Symbol: Slc9a6
Full name: solute carrier family 9 (sodium/hydrogen exchanger), member 6
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 3732426M05; 6430520C02Rik; NHE6; mKIAA0267
Summary: Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Acts upstream of or within several processes, including brain-derived neurotrophic factor receptor signaling pathway; dendritic spine development; and regulation of neurotrophin TRK receptor signaling pathway. Located in several cellular components, including axon; dendrite; and endosome. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Used to study Christianson syndrome. Human ortholog(s) of this gene implicated in Christianson syndrome. Orthologous to human SLC9A6 (solute carrier family 9 member A6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E18 (RPKM 21.8), placenta adult (RPKM 16.0) and 26 other tissues
Orthologs: human
Gene size: 54670bp
Exon count: 19