Alms1 ALMS1, centrosome and basal body associated [ Mus musculus (house mouse) ] - Gene - Data resources

236266

Alms1 ALMS1, centrosome and basal body associated [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 236266)

Symbol: Alms1

Full name: ALMS1, centrosome and basal body associated

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: bbb

Summary: Enables alpha-actinin binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cholesterol homeostasis; gamete generation; and neuron development. Predicted to be active in centriole; centrosome; and cytosol. Is expressed in several structures, including aorta; central nervous system; genitourinary system; gut; and sensory organ. Used to study Alstrom syndrome and obesity. Human ortholog(s) of this gene implicated in Alstrom syndrome. Orthologous to human ALMS1 (ALMS1 centrosome and basal body associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in testis adult (RPKM 5.1), cerebellum adult (RPKM 2.7) and 18 other tissues

Orthologs: human

Gene size: 134492bp

Exon count: 24