Full name: ADP ribosylation factor like GTPase 2 binding protein

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BART; BART1; RP66

Summary: ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in testis (RPKM 36.7), fat (RPKM 27.6) and 25 other tissues

Gene size: 8377bp

Exon count: 7