Atp2c1 ATPase, Ca++-sequestering [ Mus musculus (house mouse) ] - Gene - Data resources

235574

Atp2c1 ATPase, Ca++-sequestering [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 235574)

Symbol: Atp2c1

Full name: ATPase, Ca++-sequestering

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1700121J11Rik; ATP2C1A; BCPM; D930003G21Rik; HHD; SPCA; SPCA1; pmr1

Summary: Predicted to enable ATP binding activity; ATPase-coupled cation transmembrane transporter activity; and metal ion binding activity. Involved in Golgi calcium ion homeostasis and positive regulation of Golgi to plasma membrane protein transport. Located in Golgi cisterna membrane and cis-Golgi network membrane. Is expressed in several structures, including gut; heart; liver; lung; and mammary gland. Human ortholog(s) of this gene implicated in Hailey-Hailey disease. Orthologous to human ATP2C1 (ATPase secretory pathway Ca2+ transporting 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E18 (RPKM 19.7), frontal lobe adult (RPKM 16.1) and 28 other tissues

Orthologs: human

Gene size: 109896bp

Exon count: 31