BRD4 bromodomain containing 4 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 23476)
Source: NCBI Gene (ID 23476)
Symbol: BRD4
Full name: bromodomain containing 4
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: CAP; HUNK1; HUNKI; MCAP
Summary: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in placenta (RPKM 10.8), testis (RPKM 9.2) and 25 other tissues
Orthologs: mouse
Gene size: 97021bp
Exon count: 26