GPR161 G protein-coupled receptor 161 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 23432)
Symbol: GPR161
Full name: G protein-coupled receptor 161
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: RE2
Summary: The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017]
Expression: Broad expression in endometrium (RPKM 8.0), esophagus (RPKM 3.6) and 20 other tissues
Orthologs: mouse
Gene size: 58126bp
Exon count: 11