Hmces 5-hydroxymethylcytosine (hmC) binding, ES cell specific [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 232210)
Source: NCBI Gene (ID 232210)
Symbol: Hmces
Full name: 5-hydroxymethylcytosine (hmC) binding, ES cell specific
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Also known as: 8430410A17Rik; Srap1
Summary: Enables single-stranded DNA binding activity. Involved in double-strand break repair via alternative nonhomologous end joining and positive regulation of isotype switching. Predicted to be located in replication fork. Is expressed in several structures, including adipose tissue; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human HMCES (5-hydroxymethylcytosine binding, ES cell specific). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in limb E14.5 (RPKM 8.7), CNS E18 (RPKM 8.2) and 28 other tissues
Orthologs: human
Gene size: 22715bp
Exon count: 7