Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 231872)
Source: NCBI Gene (ID 231872)
Symbol: Aimp2
Full name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Aimp2(p38); Jtv1
Summary: Enables molecular adaptor activity. Involved in positive regulation of aminoacyl-tRNA ligase activity and protein-containing complex assembly. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of protein ubiquitination; and type II pneumocyte differentiation. Located in nucleus. Part of aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including olfactory epithelium; orbito-sphenoid; submandibular gland primordium; thymus primordium; and tooth. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in adrenal adult (RPKM 41.7), liver E14.5 (RPKM 30.1) and 28 other tissues
Orthologs: human
Gene size: 7136bp
Exon count: 4