P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 231602)
Source: NCBI Gene (ID 231602)
Symbol: P2rx2
Full name: purinergic receptor P2X, ligand-gated ion channel, 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: P2X2a; P2x2
Summary: Enables extracellularly ATP-gated cation channel activity. Involved in sensory perception of sound. Acts upstream of or within several processes, including response to ATP; skeletal muscle fiber development; and smooth muscle contraction. Located in plasma membrane. Is expressed in facial ganglion; heart; medulla oblongata basal plate mantle layer; and vagus ganglion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 41. Orthologous to human P2RX2 (purinergic receptor P2X 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 29.2), genital fat pad adult (RPKM 19.6) and 5 other tissues
Orthologs: human
Gene size: 3509bp
Exon count: 12