Fbxo2 F-box protein 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 230904)
Source: NCBI Gene (ID 230904)
Symbol: Fbxo2
Full name: F-box protein 2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Also known as: FBG1; FBX2; Fbs1; Fbs2; NFB42; Prpl4
Summary: Enables amyloid-beta binding activity and carbohydrate binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Acts upstream of or within glycoprotein catabolic process; regulation of protein ubiquitination; and ubiquitin-dependent ERAD pathway. Located in cytosol and dendritic spine. Part of SCF ubiquitin ligase complex. Is expressed in brain; testis; and vestibulo-cochlear ganglion. Orthologous to human FBXO2 (F-box protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in cerebellum adult (RPKM 35.4), cortex adult (RPKM 30.5) and 4 other tissues
Orthologs: human
Gene size: 6227bp
Exon count: 7