Zc3h12a zinc finger CCCH type containing 12A [ Mus musculus (house mouse) ] - Gene - Data resources

230738

Zc3h12a zinc finger CCCH type containing 12A [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 230738)

Symbol: Zc3h12a

Full name: zinc finger CCCH type containing 12A

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: MCPIP; MCPIP-1; Mcpip1; Reg1

Summary: Enables RNA binding activity; ribonuclease activity; and ribosome binding activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of gene expression; and negative regulation of intracellular signal transduction. Located in nucleus and rough endoplasmic reticulum. Is extrinsic component of endoplasmic reticulum membrane. Used to study primary biliary cholangitis. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human ZC3H12A (zinc finger CCCH-type containing 12A). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in large intestine adult (RPKM 23.3), spleen adult (RPKM 14.6) and 15 other tissues

Orthologs: human

Gene size: 9468bp

Exon count: 6