TPX2 TPX2 microtubule nucleation factor [ Homo sapiens (human) ]
Source: NCBI Gene (ID 22974)
Source: NCBI Gene (ID 22974)
Symbol: TPX2
Full name: TPX2 microtubule nucleation factor
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: C20orf1; C20orf2; DIL-2; DIL2; FLS353; GD:C20orf1; HCA519; HCTP4; REPP86; p100
Summary: Enables importin-alpha family protein binding activity and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; mitotic spindle; and nucleoplasm. Colocalizes with spindle pole. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in testis (RPKM 19.8), bone marrow (RPKM 18.0) and 16 other tissues
Orthologs: mouse
Gene size: 62511bp
Exon count: 18