VASH1 vasohibin 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 22846)
Source: NCBI Gene (ID 22846)
Symbol: VASH1
Full name: vasohibin 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: KIAA1036; TTCP 1
Summary: Enables actin binding activity and metallocarboxypeptidase activity. Involved in negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; and proteolysis. Acts upstream of or within several processes, including negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; and negative regulation of lymphangiogenesis. Located in apical part of cell; endoplasmic reticulum; and extracellular space. Implicated in liver cirrhosis and portal hypertension. Biomarker of liver cirrhosis. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in brain (RPKM 12.0), placenta (RPKM 11.8) and 25 other tissues
Orthologs: mouse
Gene size: 21548bp
Exon count: 10