PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E [ Homo sapiens (human) ] - Gene - Data resources

22843

PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E [ Homo sapiens (human) ]
Source: NCBI Gene (ID 22843)

Symbol: PPM1E

Full name: protein phosphatase, Mg2+/Mn2+ dependent 1E

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CAMKPN; CaMKP-N; POPX1; PP2CH; caMKN

Summary: This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Expression: Biased expression in brain (RPKM 6.5), testis (RPKM 3.8) and 3 other tissues

Orthologs: mouse

Gene size: 229326bp

Exon count: 8