DLGAP4 DLG associated protein 4 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 22839)
Source: NCBI Gene (ID 22839)
Symbol: DLGAP4
Full name: DLG associated protein 4
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: DAP-4; DAP4; DLP4; SAPAP-4; SAPAP4
Summary: The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in brain (RPKM 12.5), endometrium (RPKM 11.0) and 25 other tissues
Orthologs: mouse
Gene size: 222295bp
Exon count: 18