Wnt3 wingless-type MMTV integration site family, member 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 22415)
Symbol: Wnt3
Full name: wingless-type MMTV integration site family, member 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Int-4; Wnt-3
Summary: Enables protein domain specific binding activity. Involved in positive regulation of Wnt signaling pathway. Acts upstream of or within several processes, including axis specification; embryonic morphogenesis; and generation of neurons. Located in extracellular matrix. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; embryo ectoderm; and genitourinary system. Human ortholog(s) of this gene implicated in tetraamelia syndrome 1. Orthologous to human WNT3 (Wnt family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 13.8), limb E14.5 (RPKM 4.0) and 8 other tissues
Orthologs: human
Gene size: 43847bp
Exon count: 6