Adamts20 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 223838)
Source: NCBI Gene (ID 223838)
Symbol: Adamts20
Full name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Also known as: Adamst20; bt
Summary: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active protease. Certain mutations in this gene cause defective development of neural crest-derived melanoblasts resulting in a "belted" phenotype that is characterized by white spots in the lumbar region. [provided by RefSeq, Jul 2016]
Expression: Biased expression in CNS E11.5 (RPKM 1.8), CNS E18 (RPKM 1.4) and 10 other tissues
Orthologs: human
Gene size: 163790bp
Exon count: 41