Was Wiskott-Aldrich syndrome [ Mus musculus (house mouse) ] - Gene - Data resources

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Was Wiskott-Aldrich syndrome [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 22376)

Symbol: Was

Full name: Wiskott-Aldrich syndrome

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Wasp

Summary: Enables identical protein binding activity. Acts upstream of or within several processes, including actin filament polymerization; cellular response to interferon-gamma; and endosomal transport. Located in cell-cell junction; phagocytic vesicle; and vesicle membrane. Is expressed in brain; heart; liver; and spleen. Used to study IgA glomerulonephritis and Wiskott-Aldrich syndrome. Human ortholog(s) of this gene implicated in Wiskott-Aldrich syndrome; X-linked severe congenital neutropenia; and thrombocytopenia. Orthologous to human WAS (WASP actin nucleation promoting factor). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in thymus adult (RPKM 28.4), spleen adult (RPKM 26.0) and 11 other tissues

Orthologs: human

Gene size: 9026bp

Exon count: 12