Full name: ubiquitin specific peptidase 10

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610014N07Rik; UBPO; Uchrp; mKIAA0190

Summary: Predicted to enable cysteine-type peptidase activity; p53 binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; cellular response to interleukin-1; and negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within DNA repair and autophagy. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol; early endosome; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human USP10 (ubiquitin specific peptidase 10). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 13.5), limb E14.5 (RPKM 11.2) and 28 other tissues

Gene size: 47201bp

Exon count: 16